{"product_id":"genestra-berberis-formula-90-c","title":"Genestra Brands Berberis Formula 90 Vegan Capsules","description":"\u003cp\u003e\u003cstrong\u003eCombination of berberine extracts from natural plant sources\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTraditionally used in \u003ca href=\"https:\/\/www.natures-source.com\/collections\/herbal-supplements\"\u003eHerbal Medicine\u003c\/a\u003e as a bitter to aid digestion, to help relieve \u003ca href=\"https:\/\/www.natures-source.com\/collections\/digestive-health-supplements\"\u003edigestive\u003c\/a\u003e disturbances such as dyspepsia, and as a mild laxative\u003c\/li\u003e\n\u003cli\u003eIncludes goldenseal root extract, barberry root and stem extract, barberry root bark, Oregon grape root extract, and Oregon grape root\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBerberis Formula is a blend of barberry, goldenseal and Oregon grape extracts that are traditionally used in Herbal Medicine to help maintain gastrointestinal health. The main bioactive ingredient in these extracts is \u003ca href=\"https:\/\/www.natures-source.com\/collections\/berberine-supplements-for-weight-management\"\u003eberberine\u003c\/a\u003e.\u003csup\u003e1,2\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eRecent research demonstrates that berberine inhibits bacterial attachment to the gastric mucosa.\u003csup\u003e3\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eBerberine also mediates the transport of ions and water across intestinal epithelial cells.\u003csup\u003e3\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eIt helps maintain the balance between electrolytes and water, resulting in an anti-diarrheal effect.3 Berberine can increase the expression of the Na+; H+ exchanger and aquaporin,\u003csup\u003e2\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003ewhich help enhance the absorption of sodium and water, respectively.\u003csup\u003e3,4\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eBerberine also promotes proper \u003ca href=\"https:\/\/www.natures-source.com\/collections\/intestinal-support-supplements\"\u003eintestinal\u003c\/a\u003e epithelial tight junction formation, and decreases the permeability of these cells to promote appropriate gastrointestinal barrier function.\u003csup\u003e5\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eDuring low contractile states, berberine stimulates the jejunum through the activation of muscarinic receptors, resulting in increased intestinal motility, and a mild laxative effect.\u003csup\u003e\u003csub\u003e6\u003c\/sub\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003cbr\u003e1. Javadzadeh, SM, Ebrahimi, A. Sci. Agri. 2013; 1(2): 61-66.\u003cbr\u003e2. Siow, YL, Sarna, L, O, K. Food Research International. 2011; 44: 2409-2417.\u003cbr\u003e3. Chen, C, Yu, Z, Li, Y, Fichna, J, Storr, M. The American Journal of Chinese Medicine. 2014; 42(5): 1053-1070.\u003cbr\u003e4. Zhang, Y, Wang, X, Sha, S, Liang, S, Zhao, L, Liu, L, Chai, N, Wang, H, Wu, K. BFitoterapia. 2012; 83: 1014-1022.\u003cbr\u003e5. Gu, L, Li, N, Gong, J, Li, Q, Zhu, W, Li, J. The Journal of Infectious Diseases. 2011; 203: 1602-1612.\u003cbr\u003e6. Chen, DP, Xiong, YJ, Lv, BC, Liu, FF, Wang, L, Tang, ZY, Lin, Y. Journal of Pharmacy and Pharmacology. 2013; 65(5): 734-744.\u003c\/p\u003e","brand":"GENESTRA","offers":[{"title":"Default Title","offer_id":42264544608330,"sku":"40371","price":53.5,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0654\/3284\/6410\/files\/products_883196113224_EN_01.jpg?v=1751833498","url":"https:\/\/naturesourcedeals.myshopify.com\/products\/genestra-berberis-formula-90-c","provider":"Nature's Source USA","version":"1.0","type":"link"}